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Stroke victims often find themselves with severe damage to their speech, so doctors often refer them here for drug research. But many patients are reluctant because of the costs – up to $15,000 a month for long-term care – and the potential for addiction.
Dr. Stephen Tashkin, professor of neuroscience at Columbia, studies whether using drugs can protect the brain from strokes with some promise for treating stroke victims who lack the funds to obtain prescription drugs or can't get the right drug at a low enough price.
"We don't know if there are ways to reverse the damage with drugs alone," Dr. Tashkin says. "But we've thought about this: how do we make them stronger? How do we make the drug last longer?"
The best idea, he says, are what calls "smart drugs," which could prevent stroke. At least two drugs that mimic natural neuroregulators, a group of molecules that act like cellular power stations to protect the brain from damage when damaged, have already been tested in Strattera 10mg $77.05 - $0.64 Per pill animals. And several other small molecules known to help prevent stroke are being studied as possible anti-stroke therapies.
"We do need these drugs on a larger scale," says Dr. Tashkin, who presented research showing that one such smart drug reduced the damage caused by a stroke in people who had developed an aggressive form of cancer.
The drug was effective in reducing nerve cell damage and the loss of motor neurons — the cells that power muscles. But only when used twice a week were the effects statistically equivalent to of surgery, he says. Dr. Tashkin says plans to continue investigating smart drugs as possible treatments for stroke victims.
One idea is to combine a drug with neuroprotective substance, as researchers are doing with a compound in study about to begin the U.K. That compound, called MK-5769, was approved last December for use in mice to block the brain development of blood vessels in the br |
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